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Archive for the ‘Anti-Fungal Treatments’ Category

Promising New Anti-Fungal

A new patented new molecule, silver dihydrogen citrate (SDC), is the first new antimicrobial in decades. Developed by Pure Bioscience, SDC is an electrolytically generated source of stabilized ionic silver that can serve as the basis for a new range of products that can potentially be used to increase the efficacy of topical anti-fungal medications.

Traditional silver-based disinfectants have very short shelf lives – from hours to days. SDC is a stabilized silver ion complex with a shelf life of several years. The unique bond of the silver ion in SDC allows the silver ion to remain in solution while at the same time making it more bio-available for antimicrobial action.

SDC kills microorganisms by two modes of action: 1) the silver ion deactivates structural and metabolic membrane proteins leading to microbial death; 2) the microbes view SDC as a food source, allowing the silver ion to enter the microbe. Once inside the organism, the silver ion denatures the DNA, which halts the microbe’s ability to replicate and leads to its death. This dual action makes SDC highly and quickly effective against a broad spectrum of microbes, including fungi.

While SDC is highly toxic to bacteria, fungus and virus it is non-toxic to humans and animals. Based on the EPA toxicity categorization of antimicrobial products that ranges from Category I (high toxicity) down to Category IV, at use dilutions, SDC is rated in the lowest toxicity category IV, which makes the molecule very attractive for the development of complex anti-fungal products.

Why Medication Did Not Work

Terbinafine is perceived to be the best anti-fungal agent. Although the drug is demonstrably the most effective agent in dermatophyte onychomycosis a consistent failure rate of 30–40% is found in most studies. If the most obvious causes of treatment failure, notably poor compliance, poor absorption, imunosuppression, dermatophyte resistance and zero nail growth are excluded, the commonest cause of failure is likely to be a condition known as Subungual dermatophytoma. It is a tightly packed mass of fungus, which prevents penetration of the drug in adequate concentrations.

Patient previously treated with oral terbinafine remain susceptible to new fungal infections for an indefinite period of time. It is very frustrating for these patients to see the fungus relapse after a temporary clearance of the nails. Most of them will be reluctant to take the toxic medication again, and for obvious reasons.

The truth is: none of the monotherapies, including oral medication, the most effective one in the traditional medicine, will work against fungus. A comprehensive and long term treatment and preventive program is required to succeed in destroying fungus and keeping dermatophytes away.

Why Treatment is Required

Although dermatophyte onychomycosis is relentlessly progressive there remains a view among many patients and even some practitioners that it is a trivial cosmetic problem that does not merit treatment.

In the elderly the disease can give rise to complications such as cellulitis and therefore further compromise the limb in those with diabetes or peripheral vascular disease. While these complications may not be common they are certainly serious. The high prevalence of the disease is the result of heavy contamination of communal bathing places by infected users; disinfecting the floors of such facilities is very difficult because fungal elements are protected in small pieces of keratin. It is therefore logical to try to reduce the number of infected users by effective treatment and thus reduce disease prevalence.

Finally, onychomycosis is a surprisingly significant cause of medical consultation and of absence from work. Onychomycosis should not therefore be considered a trivial disease, and there is a sound case for treatment on the grounds of complications, public health considerations and effect on quality of life.

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Got Fungus? Get Treated!

Onychomycosis is a common fungal infection of the nails, most often the toenails. Risk factors include increasing age, diabetes, nail trauma, hyperhidrosis, peripheral vascular disease, poor hygiene, tinea pedis, immunodeficiencies and chronic exposure of nails to water.

Recent research documented a relationship among smoking, peripheral arterial disease and onychomycosis. Studies have reported the prevalence of onychomycosis to be 8 percent to 9 percent in the general population. Data obtained from a multi-center survey suggest that 26 percent of diabetics have evidence of toenail onychomycosis. The prevalence among 40- to 60-year-olds is 15 percent to 20 percent, with men being more likely to have onychomycosis than women.

Dystrophic changes of the nail include thickness, discoloration and loosening of the nail plate from the nail bed. Nail discomfort also is a feature of onychomycosis.

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Medical Treatment of Mycotic (Fungal) Nails

Fungus can spread from foot to footFungal nail infections are ugly and embarrassing. They are common and easy to catch, but very hard to get rid of. Unfortunately most people ignore them considering fungal nails a cosmetic nuisance. Fungus could be a minor bother for a while, but if left untreated, the infection will get worse: nails may grow so thick, you will feel discomfort wearing closed toe shoes, nails may separate from toes (onycholysis), the matrix can get permanently damaged (onychodystrophy)… Long story short, onychomycosis is a serious disease, which requires medical attention and a comprehensive treatment.

Nail fungus (Onychomycosis) is the most common nail disease, and over 30 million in the U.S. alone suffer from this condition. About 50% of the population over 45 years of age has nail infections. Some have battled fungi for decades.

Treatment of Onychomycosis is challenging because the infection resides in the hard-to-reach area under the nail, called the nail bed. Topical anti-fungal solutions cannot get there. Oral medications cannot target this specific area and may be toxic and hard on the liver.

New laser-assisted therapies are being developed and a growing number of foot doctors in the U.S. report excellent clinical results. To maximize the efficacy, laser treatments should be combined with a complete and comprehensive program.

Typically at least two laser treatments of all toes with a focus on the badly infected ones are required. Patients need to use a UV shoe sanitizer (yes, we have to treat all shoes to kill fungus and bacteria), a strong topical medication as well as a care regimen for prevention of re-infection. This comprehensive course of treatment is safe, non-toxic, pain-free and highly effective.

Thanks to its ability to pass through the nail and kill fungi in the nail bed, laser light is the only modality available today, which allows practitioners to address the very cause of the disease. While the high intensity light and thermal damage delivered to the target by the laser is lethal for the fungi, it is safe for the surrounding skin. In fact, these same lasers are used for new collagen growth in anti-aging aesthetic procedures and may stimulate the growth of new, healthy and fungus free nails, which will gradually replace the old ones.

Patients with mycotic nails are very susceptible to re-infections. The fungus is everywhere in the environment of the people with Onychomycosis. Therefore, the complex decontamination and preventive care regimen are critical for the success of the treatment.

To learn more about the use of lasers for fungus visit

If You Cannot Take Oral Antifungals

There is an ongoing debate among doctors about what can be prescribed for the treatment of fungal nail infections if the patient should not take oral medication due to liver, kidney or other concerns. There are at least two schools of thought on this issue.

Several formulations of topical antifungal agents are available: lacquers, solutions, creams, and gels. Traditional doctor will recommend or sell a lacquers and/or solutions for a fungal disease involving only the nail plate, and a cream or a gel when the tinea infection involves toes and feet as well as the nails. Typically these formulations have a small content of an active ingredient, and even if it’s available at the doctor’s office only, chances are the product will not produce the expected result if used alone.

Topical antifungal agents are usually not curative for onychomycosis when used as monotherapy. However they may be partially effective in improving or preventing further progression of tinea unguium in a patient with dermatophyte infection of the nails who is unable to tolerate oral antimycotic drugs.

Nail’n’Toe providers use a strong anti-fungal formulation available by prescription only through a compound pharmacy. It is part of the treatment plan, i.e. used in conjunction with other therapies customized by doctors for each individual patient.

What is Toenail Fungus (Onychomycosis)?

Onychomycosis (i.e. Toenail Fungus) is often a very uncomfortable condition that may have both physical and psychological consequences to the individual with Toenail Fungus . Onychomycosis (OM or Toenail Fungus ) is one of the fungal diseases that results from a dermatophytic invasion of the toenails. In the last few years, new oral Toenail Fungus medications and novel light source treatments have shown positive results in lowering the incidence of recurrence and side effects of the disease.

Toenail Fungus Research: What is Toenail Fungus

What is Onychomicosis or Toenail Fungus? Toenail Fungus can be referred to as a localized infection of the nail, caused by a pathogenic fungi. It is characterized by discoloration and thickening of the nail, and thus, the nails are often thick, yellow, or brittle. Toenail Fungus can cause pain and discomfort, but it is mainly a receptacle for infection (Mooney, 1993). See pictures of nails infected by fungus.

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Medication for Onychomycosis

Treatment of onychomycosis depends on the clinical type of the disease, the number of affected nails, and the severity of the case. Most doctors agree that a systemic treatment by oral medications is always required in proximal subungual onychomycosis and in distal lateral subungual onychomycosis involving the lunula region.

White superficial onychomycosis and distal lateral subungual onychomycosis limited to the distal nail can sometimes be treated with topical agents.

A combination of systemic and topical treatment increases the cure rate. Because the rate of recurrence remains high, even with newer agents, the decision to treat should be made with a clear understanding of the cost and risks involved, as well as the risk of recurrence.

Photodynamic therapy and lasers represent the most advanced treatment options.

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Will Listerine and Oils Help Rid of Toenail Fungus

listerine and tea tree oil for fungusStill hoping to get rid of nail fungus on your own in the comfort of your home?

Sorry to disappoint you, but your chances of succeeding, that is completely removing fungal spores from the nail beds of your toes and/or fingers, are lower than 10%.

Toenail fungi (aka dermatophytes) infect nails by entering through a small crack or opening, often caused by a micro injury,  in the cuticle or under the tip if the nail plate. Fungal spores thrive in the warm and moist environment of your shoes and socks, as well as other cozy places in your house.

Once a toenail has become infected, it will not go away on its own nor can you scrape or cut it away. At the onset of the infection toenails look pale and yellowish but they become increasingly darker in color, thicker and uglier as the infection progresses. The fungus will eventually damage the nail and surrounding skin tissues, causing a more severe infection accompanied by yeast infections, inflammation and soreness.

For years, homemade remedies such as Listerine have topped the list of effective toenail fungus treatments. With advances in active ingredients and improved formulation, skin care solutions may provide some relief to this disease but are unable to offer the cure.

Topical creams and applications have been developed using a combination of low potency drugs and natural oils, such as tea tree and emu oils, which may inhibit fungal growth in the skin. However nail bed is where the toenail fungus resides – safely shielded by the nail. Unfortunately, none of the topical preparations available on the market can penetrate the nail and deliver active ingredients to the target in order to destroy the fungus.

Listerine, Vicks VapoRub and their combinations with other ingredients such as Peppermint, Menthol and Grape Seed extract, are useful for cleaning and healing damaged skin tissue and help prevent reinfections. In other words, if your prime goal is to get rid of fungus in your nails you need to take a complex anti-fungal therapy, such as Nail’n’Toe, prescribed by a medical professional, and once you are fungus-free as confirmed by culture or biopsy tests, you should stick to a preventive regimen, which may include different topical preparations.

Fast and Effective Treatment for Simple Fungal Infections

tenia pedis is among easy to treat fungal infectionsAthlete’s Foot (Tinea pedis, “pedis” is the Latin word for foot), Jock itch and Ringworm, caused by a common tinea fungus infection, are not a serious concern. Tinea is a fungus that can grow on your skin, hair or nails. As it grows, it spreads out in a circle, leaving normal-looking skin in the middle. This makes it look like a ring. At the edge of the ring, the skin is lifted up by the irritation and looks red and scaly.

Tinea infection may look like a worm under the skin – thus the term “ringworm.” However, there really isn’t a worm under the skin. Symptoms include itching, burning and cracked, scaly skin.

Tinea grows best in damp, dark and warm places, which is why it often develops between your toes. If left untreated these types of tinea may spread to your toenails, making them thick and crumbly. This is called tinea unguium — “unguium” comes from the Latin word for nail. It can spread to your hands and fingernails.

You can get tinea infections from damp surfaces, such as locker room floors and public beach showers.

Treatments include over-the-counter antifungal creams for most cases and prescription medicines for more serious infections.

A fungus rarely spreads below the surface of the body to cause serious illness. Your body usually prevents this. Tinea infections usually don’t leave scars after the fungus is gone. However, people who have weak immune systems, such as people who have HIV or AIDS, may have a hard time getting rid of a fungal infection.